Susceptibility testing of Haemophilus influenzae to clarithromycin

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Susceptibility testing of Haemophilus influenzae to clarithromycin.

Susceptibility testing of Haemophilus influenzae to the macrolide compounds has often been problematic. This is as a result of the inability of many isolates of H. influenzae to grow without the addition of 5% CO2 to the incubation atmosphere and the subsequent detrimental effect that CO2 has on the activity of the macrolide group of compounds. This report describes refinements and recommendati...

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Selected clinical isolates of Haemophilus influenzae were tested for their susceptibility to seven antibiotics by a microtiter broth dilution and an agar diffusion method. Eleven of 40 strains tested were resistant to ampicillin, the drug of choice, by both methods. All the strains tested were susceptible to chloramphenicol, and all but one were susceptible to tetracycline. Of the other four an...

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Quantitative antibiotic susceptibility testing: Haemophilus influenzae type B.

Twelve strains of Haemophilus influenzae were tested for susceptibility to gentamicin, ampicillin, chloramphenicol and cephalothin using two methods, agar dilution and microdilution (broth). Although inocula and incubation conditions were standardized, significant differences in the minimal inhibitory concentration (MIC) were seen as a result of growth media. Method dependent differences were a...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2000

ISSN: 0305-7453,1460-2091

DOI: 10.1093/jac/45.4.529